The reader of Animal Sentience may surmise that because the weight of the commentaries on my target article, “Why fish do not feel pain,” is leaning towards not supporting my argument, it follows that the premise fish do not feel pain is incorrect. However, science does not prevail by popular opinion. History is plagued with numerous (and often widely accepted) examples of biological phenomena being explained by mysterious forces. In the absence of a mechanistic understanding, the many different guises of vitalism (the principle that life involves a vital energy) are often invoked to explain the unknown. Spurious assumptions tend to exist when there is ignorance and misunderstanding of mechanisms. The most effective way to argue against c...